Article published the 30 May. 2016
The Sens-is sensitization test, initially developed by Immunosearch, is based on the use of a reconstructed skin model (Episkin®) and the evaluation by RT-PCR of the expression of 62 genes selected as being relevant in the biological sensitization process.
While most tests currently available for the assessment of sensitization only give a qualitative response, Sens-is is the only test giving a quantitative response that correlates with the mouse model of LLNA (OECD TG 429) .
Advantages of the Sens-is test
- Quantitative assessment in correlation with the LLNA
- Episkin ® reconstituted epidermis
- Currently being validated by the OECD
Sens-is compared to other tests
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