CBM - CENTRE DE BIOPHYSIQUE MOLÉCULAIRE

RESEARCH AND TRAINING

PUBLIC RESEARCH LABORATORIES

BIOLOGIE

Activity

Interest in cosmetic perfumery

• Cell biology, cell imaging, cell tools, new 3D cell models in a controlled atmosphere, skin microenvironment,
• Glycobiology, microRNAs
• Membrane receptors and signalling, molecular interactions, targeting of molecules of interest
• Peptides, glycopeptides, liposomes and polymers
• Vectorisation, innovative formulation and skin penetration
• Molecular physicochemistry

Research topic

Development of research at the interface between chemistry, biology and physics, using in vitro, in silico, in cellulo and in vivo approaches, focusing on the molecular mechanisms of living organisms and their dysregulation leading to the development of diseases:
• Molecular aspects of life
• Receptor biology and biophysics: translational applications
• Chemistry, imaging and exobiology
• Theoretical and computational biophysics
• Nanodrugs

Experimental means

• Cell culture: controlled atmosphere incubators, UV irradiator, imager
• qPCR-dropletPCR, WesternBlot analysis, microplate readers (absorbance, fluorescence, luminescence, alphascreen, BRET, FRET), histology platform
• IBISA MO2VING platform: Confocal microscope, videomicroscopes / Flow cytometry, cell sorter / 400, 600 and 700 MHz NMR / MRI-MRS (horizontal magnet 7 Teslas and 9.4 Teslas) / Mass spectrometers (ES-triple quad, Maldi-Tof, ES ion traps)Confocal RAMAN spectrometer / Atomic force microscope (AFM) / Fluorescence and circular dichroism spectrometers / X-ray generator / STORM phosphorimager / Differential scanning microcalorimeter

Contact details

Adress

UPR 4311 CNRS - RUE CHARLES SADRON

45100

Orléans

Contact

Website

http://cbm.cnrs-orleans.fr/

Contacts

Établissement

CNRS

3E AVENUE DE LA RECHERCHE SCIENTIFIQUE

45100

Orléans

+33 2 38 25 52 00

Connection